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Study Reveals Cannabis Terpenes as a Promising Alternative for Neuropathic Pain Relief

A recent study in the journal Pain sheds light on the potential of cannabis terpenes in alleviating chemotherapy-induced neuropathic pain, presenting a side-effect-free alternative to traditional treatments. John Streicher, PhD, from the Comprehensive Center for Pain & Addiction at the College of Medicine – Tucson, spearheaded the research, which investigated the efficacy of terpenes in a mouse model of neuropathic pain resulting from chemotherapy-induced nerve damage.

The findings indicated that individual terpenes exhibited comparable effectiveness to morphine in reducing chronic neuropathic pain, with a synergistic effect emerging when terpenes combined with morphine. This combination not only enhanced pain relief but also mitigated negative side effects commonly associated with opioid analgesics.

According to Streicher, the study explored various aspects of terpenes to assess their impact on reward mechanisms, addiction potential, and overall well-being. The results suggested that terpenes not only effectively relieved pain but also demonstrated a favorable side effect profile, paving the way for considering combination therapies that could enhance pain management while reducing the addictive properties of opioids.

The research, titled “Terpenes from Cannabis sativa induce antinociception in a mouse model of chronic neuropathic pain via activation of adenosine A2A receptors,” represents a significant contribution by examining the pain-relieving potential of terpenes and their associated side effects in the realm of neuropathic pain management.

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